I don't use a visual nocking point any more -- meaning a knot, etc. on the string. I just place the arrow slightly above square to the string visually. I think I probably adjust the actual nocking point unconsciously depending on how the last arrow flew. Strings can change, and so can limbs for various reasons, humidity, etc. So my guess is I may not be nocking at the exact same point every time I string the bow. This didn't answer DC's question. But it's a preface to why I have an opinion about it, and what that opinion comes from.
In shooting a new character bow with asymmetric limbs I built early on, I found that I needed a low knock point, rather than the more standard slightly high one to get decent arrow accuracy. But the feathers did hit the hand fairly hard. If I tried to nock higher, the flight suffered.
Because the limbs were asymmetric, I wasn't sure what to do to correct this problem. Since the bow was also under weight, I was not keen to tiller either limb further. I was thinking of piking one limb as a possibility. But didn't know which one to pike. Before I did that, though, I tried shooting the bow upside down, and was surprised to get accurate shots and a normal square to the string nocking point, and light feather contact.
Unfortunately the handle had been carved biased to gripping the other way round. What really surprised me though was that the upper limb was now shorter than the lower, and if you figure in the movement of the location of the arrow pass on the bow the effective length of the upper limb was greatly reduced.
What I wasn't counting on was that the grip was forcing a lower contact point than I had been using before, which was more of a pinch.
Sorry DC, I'm still not answering your question. Because I'm still not sure of the answer to the specific of it. But what I did learn then, was that the handle shape can greatly affect the arrow flight and nocking point, and degree of limb asymmetry, too.
I'm sure this is obvious to the more experienced here, and they have settled on handle shapes and arrow pass location which they repeat consistently, so it doesn't become a question. And then setting a nock point at a specific distance that they have found through experience works best is consistent with that set of givens. But I think it's not possible to separate nocking point, limb symmetry, tillering, handle shape for bows built by different and less experienced people.
If you think about it, bow-hand fletching contact, and arrow flight are two different effects, both of which may be altered independent of each other by raising or lowering a nock point on the string. So a single answer -- tiller or pike one or the other limb -- might not solve the problem, or might induce another, if the grip or symmetry is a cause.
I have to admit that lately I have been building symmetric length limbed bows, and I am paying particular attention to how the grip hits my hand. And, at least for me, the results tillering and shooting have become more consistent.
Sorry to add one more non-answer here to your very direct and simple seeming question.