Well, thanks for the advice everyone.  I finished it up a couple months ago, put about 300 arrows through it so far. 
Took about 1-3/4" of set - I didn't put reflex in it before applying sinew, and I only put one layer on it - both of which I regret after seeing how much set it took.
I recently read that you should tiller from the tips in - something I'll be doing from now on. I think that was a factor in the set, as well as tillering in humid conditions, and the narrow profile. 
Overall though, pretty happy the way it turned out.  Pulls about 45# at 27".  Tips are a bit stiff but I didn't want to compromise weight anymore. 
Pretty much the first legit bow I've made, so pretty stoked!