If the string is favoring the side your arrow rests I wold leave it personally, then your arrow spine wouldnt be as critical as it wouldnt have to flex around the grip as much, you may get more arm slap though. If its to the opasite side then I would heat it at the grip and then put a block on both sides of the grip and clamp the grip to bring the string into alighnment. Other may do it differently so I would get more feedback and then decide what you want to do.
Josh