I think this bow would be up for the challenge!  
I envision a serious set of arrows to go with it, after all it's the arrow that carries the mail.  I would envision something with decent weight, like 750 grains or more.  Tapered shafts because I firmly believe heavy hunting arrows need tapering to put even more weight forward so they recover faster off the string and fly straighter.  Then I would look for a heavy broadhead, two blade only, and definitely sharpened to a single bevel...185 grain broadhead so there is plenty of kinetic energy on impact.  Those moose are famous for a thick hide in the shoulders, so cut-on-contact is absolutely non-negotiable.  The single bevels having such a wicked point and super shallow cutting angle really starts to show off it's best character.  Moose hunting can be a very close range sport, the deeper the penetration and the greater the chance of a thru-and-thru the happier I'd be when I dropped the string.  
That and the ability to levitate on demand.  Moose ain't exactly shy about their feelings. 
Best of luck to your hunting buddy!